全球健康中心的教职员工、研究员和学生开展研究，以解决困扰资源贫乏国家人民的主要健康问题。调查人员确定健康问题的严重程度和根本原因，然后设计、测试和实施挽救生命的干预措施。例如，海地的威尔康奈尔医学院于1982年发现并描述了发展中国家的第一例艾滋病病例。然后，他们进行了新的艾滋病毒预防策略和治疗方法的临床试验。35年后，海地总人口的艾滋病毒流行率从6%下降到2%以下。70%的艾滋病毒感染者目前正在接受有效治疗。
教育是全球健康中心的核心，该中心为威尔康奈尔医学院、康奈尔大学和国际合作伙伴的学生和博士后研究员提供课堂、实验室和现场培训。威尔康奈尔医学院的海外教师在国际站点协调国际和WCM学生，实习生和居民的教学和培训。该中心还支持在纽约威尔康奈尔医学院学习的国际学者，同时继续在本国进行研究项目。在过去的十年中，他们有来自巴西，海地，坦桑尼亚和印度的24名医生获得了威尔康奈尔医学临床流行病学硕士学位。
他们所有的国际伙伴都为本国的穷人提供保健服务。例如，Weill Bugando的医生为坦桑尼亚西部的800张床位的转诊医院工作，该医院为1500万人口提供服务。威尔康奈尔医学院的医生除了应对自然灾害和突发公共卫生事件（如地震、飓风、霍乱流行和炭疽爆发）外，还提供临床培训和床边教学。
Faculty members, researchers, and students at the Center for Global Health conduct research to address the major health problems plaguing people in under-resourced countries. Investigators determine the severity and root cause of health problems, then design, test, and implement life-saving interventions. In Haiti, for example, the Weill Cornell Medical College in Haiti detected and described the first case of AIDS in a developing country in 1982. They then conducted clinical trials of new HIV prevention strategies and treatments. Thirty-five years later, the HIV prevalence rate of the total population of Haiti has declined from 6 per cent to less than 2 per cent. Seventy per cent of people living with HIV are currently receiving effective treatment.
Education is at the heart of the Center for Global Health, which provides classroom, lab, and field training to students and postdoctoral fellows at Weill Cornell Medical College, Cornell University, and international partners. Weill Cornell Medical College's overseas faculty coordinate the teaching and training of international and WCM students, interns, and residents at international sites. The center also supports international scholars studying at Weill Cornell Medical College in New York while continuing research projects in their home countries. Over the past decade, they have 24 physicians from Brazil, Haiti, Tanzania and India who have earned a master's degree in clinical epidemiology from Weill Cornell Medicine.
All their international partners provide health services to the poor in their countries. For example, doctors at Weill Bugando work for an 800-bed referral hospital in western Tanzania, which serves a population of 15 million. In addition to responding to natural disasters and public health emergencies such as earthquakes, hurricanes, cholera epidemics, and anthrax outbreaks, doctors at Weill Cornell Medical College provide clinical training and bedside teaching.