威尔康奈尔医学院神经遗传学中心调查基因以及环境与基因组的相互作用对儿童和成人神经系统疾病发展的影响。作为威尔康奈尔大学Feil家族脑与心研究所的一部分,该中心是整个学院的研究中心,临床医生,基础科学家,病理学家,分子生物学家和计算机科学家合作,帮助诊断和治疗受遗传影响的神经系统疾病患者。研究人员共同推进威尔康奈尔医学院为患者所做的努力,并为全世界对神经系统疾病的遗传基础的理解做出贡献。
该中心的使命是追求基因突变、序列变异、基因组调控和表观遗传修饰对人类基因组在神经系统健康和疾病中的运作的贡献。
该中心正处于一场革命之中,以了解神经系统疾病(如癫痫、精神分裂症、自闭症和痴呆)背后的遗传成分。准确确定哪些遗传改变导致神经系统疾病,以及DNA水平的差异如何转化为可观察到的神经系统疾病,至关重要。威尔康奈尔医学院的神经遗传学中心处于这项研究的前沿,与患者合作,了解他们的疾病起源和可用的治疗方法,帮助家庭发现遗传风险,并创建一个知识库,推进研究和开发未来的神经系统疾病治疗方法。
The Center for Neurogenetics at Weill Cornell Medical College investigates the effects of genes, as well as environment-genome interactions, on the development of neurological disorders in children and adults. As part of the Weill Cornell University's Feil Family Brain and Heart Institute, the center is a college-wide research center where clinicians, basic scientists, pathologists, molecular biologists, and computer scientists collaborate to help diagnose and treat patients with neurological disorders affected by genetics. Together, the researchers advance Weill Cornell Medical College's efforts for patients and contribute to the world's understanding of the genetic basis of neurological disorders.
The mission of the Center is to pursue the contributions of genetic mutations, sequence variations, genomic regulation, and epigenetic modifications to the functioning of the human genome in neurological health and disease.
The center is in the midst of a revolution to understand the genetic components behind neurological disorders such as epilepsy, schizophrenia, autism and dementia. Determining exactly which genetic alterations cause neurological disorders, and how differences in DNA levels translate into observable neurological disorders, is critical. Weill Cornell Medical College's Center for Neurogenetics is at the forefront of this research, working with patients to understand their disease origins and available treatments, helping families discover genetic risks, and creating a knowledge base that advances research and development of future treatments for neurological disorders.