斯坦福大学肖恩·n·帕克过敏和哮喘研究中心是同类中心中的首个中心，不仅旨在为患有过敏和哮喘的儿童和成人找到更好的治疗方法，而且还旨在发现对抗这些疾病的潜在免疫机制，并开发出一种持久的治疗方法，通过创新的科学和富有同情心的护理来改变患者和家属的生活。
Kari Nadeau博士是美国成人和儿童过敏和哮喘方面最重要的专家之一，也是中心的主任，在她的带领下，该跨学科中心专注于了解免疫系统的机制（免疫系统的功能障碍导致过敏反应）。作为过敏研究的领导者，该中心与世界各地的其他研究人员合作，从他们相互关联的卫星中心创建一个数据共享信息集群，以开展过敏研究的新颖和创新的临床试验。
该中心包括斯坦福大学各个领域的专家，包括免疫学、胃肠病学、耳鼻喉科、化学、生物工程、病理学、肺病学和遗传学，通过实验室和计算研究、临床试验、社区外展和其他努力，该团队致力于寻找基于理性的治疗方法，为过敏和哮喘提供最安全和最好的治疗方法。该中心的研究可能对一系列广泛的免疫功能障碍产生影响，包括哮喘、湿疹、食物过敏、嗜酸性粒细胞失调、药物过敏、胃肠疾病等等。
该中心领导或参与了许多临床试验，以开发针对过敏性疾病的新疗法，他们的研究涵盖了广泛的患者，代表了不同的种族和社会经济背景，他们为所有过敏和哮喘患者提供平等的机会，只要他们符合研究参数的条件。
中心主要的研究方向是食物过敏研究：
通过口服免疫疗法（OIT）脱敏和耐受的免疫机制——他们正在研究不同免疫细胞亚群的潜在作用，这对于实现对食物过敏原的脱敏和最终耐受（持续无反应）非常重要，这是使用来自接受不同免疫疗法的食物过敏研究参与者的血液和组织样本进行研究的。
开发更好、更安全的食物过敏诊断工具——口服食物激发试验（OFC）是目前食物过敏临床诊断的金标准，对患者安全提出了挑战，需要广泛的临床监督。他们正在与斯坦福大学生物工程系的同事合作，开发采用微流体和蛋白质组学的新方法和工具。
食物过敏双胞胎的表观遗传因素——他们正在检查食物过敏的双胞胎的免疫细胞，以更好地了解导致食物过敏发展和进展的表观遗传因素。
The Sean N. Parker Center for Allergy and Asthma at Stanford is the first of its kind and aims not only to find better treatments for children and adults with allergies and asthma, but also to discover the underlying immune mechanisms that fight these diseases and develop a long-lasting treatment. Transforming the lives of patients and families through innovative science and compassionate care.
Under the leadership of Dr. Kari Nadeau, one of the foremost experts in allergy and asthma in adults and children in the United States and director of the Center, the interdisciplinary center focuses on understanding the mechanisms of the immune system (dysfunction of the immune system that leads to allergic reactions). As a leader in allergy research, the Center collaborates with other researchers around the world to create a data-sharing information cluster from their interconnected satellite centers to conduct novel and innovative clinical trials in allergy research.
The center includes Stanford experts in a variety of fields, including immunology, gastroenterology, otolaryngology, chemistry, bioengineering, pathology, pulmonology, and genetics, and through laboratory and computational research, clinical trials, community outreach, and other efforts, the team is committed to finding rational-based treatments that will provide the safest and best treatment for allergies and asthma. The center's research may have implications for a wide range of immune disorders, including asthma, eczema, food allergies, eosinophilic disorders, drug allergies, gastrointestinal disorders, and more.
The Center has led or participated in many clinical trials to develop new therapies for allergic diseases, and their research covers a wide range of patients, representing diverse ethnic and socioeconomic backgrounds, and they offer equal access to all allergy and asthma patients, as long as they meet the conditions of the study parameters.
The main research areas of the Center are food allergy research:
Through the immune mechanisms of oral immunotherapy (OIT) desensitization and tolerance, they are investigating the potential role of different immune cell subsets, which are important for achieving desensitization and ultimate tolerance (persistent non-response) to food allergens, using blood and tissue samples from food allergy study participants who received different immunotherapies.
Develop better and safer diagnostic tools for food allergies. Oral food provocation testing (OFC), the current gold standard for clinical diagnosis of food allergy, presents challenges to patient safety and requires extensive clinical oversight. They are working with colleagues in Stanford's Department of Bioengineering to develop new methods and tools that employ microfluidics and proteomics.
Epigenetic factors in twins with food allergy. They are examining immune cells from twins with food allergies to better understand the epigenetic factors that contribute to the development and progression of food allergies.